Indicated to collect tissue samples from the bronchi and/ or upper lower gastrointestinal tracts of the diagnosis of suspected pathology in the airways. Tube within a tub design. The outer tube has a water soluble glycol plug in the distal end to protect the inner lumen brush from contamination as it travels through the endoscope channel. When the sample site is reached, the forward motion of the inner tube safely expels the plug, and deploys the brush. After sample collection, the brush is retracted into the outer tube, and removed from the scope channel.